The Beneficial Effects ~

of Collagen

SKIN

According to the independent scientific public authority, the Haute Autorité de Santé (HAS), collagen improves the elasticity, hydration, radiance, and firmness of the skin and hair. It slows skin damage caused by harmful external factors and helps reduce wrinkle formation. Evans et al. evaluated 85 women aged 45 to 60 in a 12-week randomized clinical trial. By administering 10 g of hydrolyzed collagen, the authors observed improved elasticity, increased firmness, and a reduction in the appearance of wrinkles. A meta-analysis conducted by Choi et al. showed that daily consumption of hydrolyzed collagen for more than three months improved nail growth, making them less brittle. Another clinical study revealed an increase in hair density in 74% of women who consumed hydrolyzed collagen for 90 days.

Skin and Sun: UV rays can damage the structure of collagen, leading to a loss of elasticity and firmness in the skin. Over time, this can cause premature skin aging, the appearance of wrinkles, and changes in skin texture. Sun exposure generates free radicals in the skin, creating oxidative stress that breaks down collagen and prevents its normal production and renewal. Collagen supplementation may act as protection against the harmful effects of the sun, offering a defense against excessive ultraviolet (UV) exposure, especially during holidays.

Several scientific articles, which require further research, highlight potential collagen benefits on multiple levels; however, these claims remain contested by health authorities:

JOINTS

Joint discomfort, often accompanied by pain, reduces mobility and the ability to perform daily tasks, directly affecting quality of life—especially when it impacts the hips, knees, or lower back. Collagen stimulates the production of cartilage and bone cells, improves bone density, and reduces joint pain associated with osteoarthritis and other musculoskeletal conditions. Most interventional clinical studies show a significant reduction in pain compared to placebo/control groups, as well as immediate improvements in joint stiffness and mobility, with beneficial effects on joint stability and recovery. Clinical studies have also shown a reduction in joint pain among athletes following collagen supplementation.

BONES

According to the independent scientific public authority, the Haute Autorité de Santé (HAS), collagen improves the elasticity, hydration, radiance, and firmness of the skin and hair. It slows down skin damage caused by harmful external factors and supports the reduction of wrinkle formation. Evans et al. evaluated 85 women aged 45 to 60 in a 12-week randomized clinical trial. By administering 10 g of hydrolyzed collagen, the researchers observed improvements in elasticity and firmness, along with a reduction in the appearance of wrinkles. A meta-analysis by Choi et al. showed that daily intake of hydrolyzed collagen for over three months improved nail growth and reduced brittleness. Another clinical study reported a 74% increase in hair density in women who consumed hydrolyzed collagen for 90 days.

TENDONS

Collagen also accounts for between 65% and 80% of the dry weight of tendons. Collagen cross-links help tendons withstand impact stress and high shear forces. Thus, collagen plays a key role in maintaining tendon health and reducing the risk of sports-related injuries.

MUSCLES

Oikawa et al. found no difference in muscle collagen protein synthesis after the consumption of collagen or whey protein, with a significant increase observed following exercise. This suggests that the overall profile of proteins and amino acids may have a greater influence than the type of protein on the synthesis of muscle proteins and collagen.

Collagen ~

as a Dietary Supplement

For collagen to be easily absorbed and utilized by our body as a dietary supplement, it must be hydrolyzed into peptides, or even into amino acids. Thanks to its low molecular weight of approximately 2000 Daltons, hydrolyzed collagen is rapidly digested by the body and reaches the bloodstream within 30 minutes after ingestion, particularly in liquid or powder form.

With the approval of health authorities, scientific data has shown that supplementation with hydrolyzed collagen amino acids (HCAA) can:

  • Promote skin changes such as wrinkle reduction, increased skin elasticity, enhanced hydration, and increased collagen content, density, and synthesis—factors closely related to skin damage associated with aging.

Several scientific articles, which require further research and are still debated by health authorities, suggest that collagen may:

  • Increase bone strength, density, and mass; improve joint mobility and functionality; and reduce pain (strong evidence for a dosage of 5 to 15 g/day).
  • Improve body composition, muscle strength, and recovery.
  • A daily dose of 15 g of HCAA has proven more effective than 5 g/day in stimulating collagen synthesis, suggesting that 15 g/day may be a more optimal dose. HCAA should ideally be consumed about 60 minutes before exercise to maximize collagen synthesis.
  • Modestly but significantly improve muscle recovery thanks to HCAA.

Finally, physical exercise and vitamin C appear to support collagen synthesis.

The Golden Rules

Of Collagen

Essential Guidelines to Maximize Collagen Effectiveness and Quality

  • The minimum effective dose is 10 grams per serving.
  • The maximum authorized dose is 20 grams per serving.
  • The higher the collagen concentration, the more intense the product’s flavor.
  • It is the increase in protein concentration that raises the cost of the formulation. Cheaper collagen generally means an insufficient protein concentration.
  • The required hydrolysis level for maximum absorption is 2000 Daltons.

These rules, along with our philosophy of high-quality products, are what determine the final composition of our formulations.

RenessisMed, where science meets nature

Each and every formula contains ingredients in the dosages that will do the most for your skin right now. Your formula keeps changing as your skin changes!